Tylenol (acetaminophen) is an analgesic, while ibuprofen (Advil, Motrin) is a nonsteroidal anti-inflammatory drug (NSAID). Tylenol and ibuprofen are both used to treat pain, inflammation, and fever, but they are not the same medication. Tylenol is the brand name for acetaminophen, an analgesic (pain reliever) and antipyretic (fever reducer NSAIDs have different properties. Tylenol, for example, can help with a headache and fever but not the inflammation that Advil can address. Naproxen is the strongest of the OTC NSAIDs, which include: Advil, Motrin (ibuprofen) Aleve, Naprosyn (naproxen) Bayer, Ecotrin, Bufferin (aspirin) Tylenol ( acetaminophen) Despite ibuprofen having a wide safety margin, it is possible to overdose on it, but death from ibuprofen overdose is rare. Children are more susceptible to the effects of ibuprofen and likely to experience an overdosage of ibuprofen if dosages of more than 400mg/kg (in the range of 8000mg for a 20kg child [the equivalent of 40 x 200mg ibuprofen tablets]) are ingested. Uses. Ibuprofen is used to relieve pain from various conditions such as headache, dental pain, menstrual cramps, muscle aches, or arthritis. It is also used to reduce fever and to relieve minor Aspirin is an NSAID that works similarly to ibuprofen. But it’s also a blood thinner. Aspirin can help reduce fever, pain, and inflammation. But it tends to have more side effects than ibuprofen and Tylenol when used for a sore throat. A typical aspirin dose for adults is 325 mg to 500 mg every 4 hours as needed. Serious side effects of ibuprofen. Serious side effects of ibuprofen are also possible. Stop taking ibuprofen, and inform your doctor right away if you experience: Breathing problems: shortness of breath or difficulty breathing. Skin issues: rash, hives, blisters, yellowing of the skin, pale skin, or itching. .

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